Pyruvic acid and vitamin B1 deficiency

Vitamin-B1 Deficiency

Lxxx. Blood Pyruvate in Vitamin B1 Deficiency

IN the course of recent work on the role of vitamin B, in the metabolism of brain, it was discovered [Peters and Sinclair, 1933] that lactate solutions in which avitaminous pigeon's brain cells had respired for 2 hours gave a positive nitroprusside reaction for pyruvic acid [Simon and Piaux, 1924]. This led to a quantitative investigation of the formation of pyruvic acid during the respiration ...

Clxxxviii. Studies on the Metabolism of Pyruvic Acid in Normal and Vitamin B1-deficient States v. the Effect of Exercise on Blood Pyruvate in Vitamin B1 Deficiency in Man

FOLLOWING the establishment [Platt & Lu, 1939] of the occurrence of increased amounts of pyruvic acid in the body fluids of patients suffering from beri-beri and the studies of Lu [1939] on the effect of muscular activity on the blood pyruvate of the rabbit, it appeared desirable that an investigation should be made of the relationships between pyruvic acid accumulation in the blood, amount of ...

Vitamin D deficiency and stroke

Vitamin D comprises a group of fat-soluble pro-hormones, obtained from sun exposure, food, and supplements, and it must undergo two hydroxylation reactions to be activated in the body. Several studies have shown the role of vitamin D in mineral metabolism regulation, especially calcium, phosphorus, and bone metabolism. Some factors such as inadequate vitamin intake and liver or kidney disorders...

Vitamin B1

Vitamin B1 is a watersoluble vitamin. It consists out of a pyrimidineand a thiazol ring, which are synthesized independently and linked afterwards.Vitamin B1 is de novo produced by many plants and microorganisms. Humans and animals have to take it up by nutrition. They are only able to do the phosphorylation reaction of the thiamin molecule. Thiamin is found free and as mono-, diand triphosphat...